Breast and Lung Cancers are global problems. In the U.S. nearly one in eight women will develop Breast Cancer in their lifetime. Lung cancer is the leading cancer killer worldwide. There is an unmet need for targeted therapy for highly aggressive triple negative Breast Cancer as well as for non-small cell and small cell lung cancers. JAA-F11 can meet these needs targeting 88% of all Breast Cancer (competitor Herceptin targets only 25% with Her-2) and 84% of lung cancers.
Our technology will enable diagnostic imaging of lung cancers and treatment of primary and metastatic breast and lung cancers by directly killing cancer cells. hJAA-F11, in addition to direct killing, has long term potential to block metastasis, thereby extending patient survival. JAA-F11 is expected to be safe as humans have small amounts of naturally occurring antibody to the TF-Ag.
De-risking and validation through the non-dilutive partnership with the NCI Experimental Therapeutics (NExT) program provides For-Robin with resources to bring hJAA-F11 through the FDA IND to first in human clinical imaging trials, by Fall of 2023.
For-Robin is seeking partner(s) and investors to support extended Phase I clinical trials in lung and breast cancer therapy with humanized JAA-F11 antibody (hJAA-F11).